Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576598 | 0.77 | KDM4E (0.34) | BRD4LRRK2NOTUMHPGD | |
| SCHEMBL24922486 | 0.74 | LRRK2 (0.36) | BRD4LRRK2NOTUM | |
| SCHEMBL24921502 | 0.74 | NPC1 (0.40) | BRD4LRRK2HPGD | |
| SCHEMBL15599482 | 0.74 | BRD4 (0.40) | BRD4NOTUMHPGD | |
| SCHEMBL24922483 | 0.70 | NOTUM (0.39) | NOTUMHPGD | |
| SCHEMBL24922505 | 0.69 | — | — | |
| SCHEMBL24922481 | 0.69 | ACHE (0.40) | LRRK2 | |
| SCHEMBL24921486 | 0.68 | BRD4 (0.34) | BRD4LRRK2 | |
| SCHEMBL10068343 | 0.67 | NOTUM (0.38) | BRD4NOTUMHPGD | |
| SCHEMBL24922527 | 0.67 | L3MBTL1 (0.42) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |