SCHEMBL2492265

SCHEMBL2492265

Cc1ncnc(O)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12825489 0.83
SCHEMBL874203 0.80
SCHEMBL6718290 0.76
SCHEMBL2493955 0.76
SCHEMBL30229716 0.76
SCHEMBL12506114 0.76
SCHEMBL8201056 0.74
SCHEMBL1628118 0.72
SCHEMBL25036986 0.72
SCHEMBL1368468 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605394-A1 PYRIMIDINE SGC STIMULATORS Tisento Therapeutics Inc. (US) 2025-08-27 EP disclosed
WO-2024086179-A1 PYRIMIDINE SGC STIMULATORS TISENTO THERAPEUTICS, INC. (US) 2024-04-25 WO disclosed
US-20230219940-A1 PROCESS FOR THE PREPARATION OF FLUOXASTROBIN AND INTERMEDIATES THEREOF UPL LTD (IN) 2023-07-13 US disclosed
EP-2906555-B1 PROCESS FOR THE PREPARATION OF VORICONAZOLE AND ANALOGUES THEREOF PFIZER IRELAND PHARMACEUTICALS (IE) 2016-12-14 EP disclosed
US-9499520-B2 Process for the preparation of voriconazole and analogues thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-11-22 US disclosed
US-9499520-B2 Process for the preparation of voriconazole and analogues thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-11-22 US disclosed
US-20160229842-A1 Process for the Preparation of Voriconazole and Analogues Thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-08-11 US disclosed
US-20160229842-A1 Process for the Preparation of Voriconazole and Analogues Thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-08-11 US disclosed
US-9388167-B2 Process for the preparation of voriconazole and analogues thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-07-12 US disclosed
US-9388167-B2 Process for the preparation of voriconazole and analogues thereof PFIZER IRELAND PHARMACEUTICALS (IE) 2016-07-12 US disclosed
US-20090312312-A1 Heterobicyclic Metalloprotease Inhibitors ALANTOS PHARMACEUTICALS HOLDING, INC. (US) 2009-12-17 US disclosed
US-20090137547-A1 Heterobicyclic metalloprotease inhibitors ALANTOS PHARMACEUTICALS HOLDING, INC. 2009-05-28 US disclosed
US-20090137547-A1 Heterobicyclic metalloprotease inhibitors ALANTOS PHARMACEUTICALS HOLDING, INC. 2009-05-28 US disclosed
US-20090062310-A1 DEUTERIUM-ENRICHED VORICONAZOLE PROTIA, LLC (US) 2009-03-05 US disclosed
US-20090062310-A1 DEUTERIUM-ENRICHED VORICONAZOLE PROTIA, LLC (US) 2009-03-05 US disclosed
US-20080221092-A1 Heterobicyclic metalloprotease inhibitors BLUHM HARALD 2008-09-11 US disclosed
US-20080221092-A1 Heterobicyclic metalloprotease inhibitors BLUHM HARALD 2008-09-11 US disclosed
WO-2008063669-A1 HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS ALANTOS PHARMACEUTICALS HOLDING, INC. (US) 2008-05-29 WO disclosed
US-20070155738-A1 Heterobicyclic metalloprotease inhibitors ALANTOS PHARMACEUTICALS, INC. 2007-07-05 US disclosed
US-20070155738-A1 Heterobicyclic metalloprotease inhibitors ALANTOS PHARMACEUTICALS, INC. 2007-07-05 US disclosed