SCHEMBL6718290

SCHEMBL6718290

Cc1ncnc(O)c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30229716 1.00
SCHEMBL2232292 0.85
SCHEMBL862484 0.78
SCHEMBL2493955 0.78
SCHEMBL2492265 0.76
SCHEMBL857430 0.74
SCHEMBL503752 0.74
SCHEMBL31032243 0.74
SCHEMBL179573 0.74
SCHEMBL6719975 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326389-B1 Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES (JP) 1996-09-11 EP claimed
US-4935516-A Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES, LTD. (JP) 1990-06-19 US claimed
EP-0326389-A2 Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES, LTD. (JP) 1989-08-02 EP claimed
US-20250313554-A1 PTPN2 INHIBITORS MONDEGO BIO, LDA. (PT) 2025-10-09 US disclosed
WO-2024145245-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2024-07-04 WO disclosed
CN-115702234-A Environment-friendly solvent, and washing composition and washing device comprising same 株式会社LG生活健康 2023-02-14 CN disclosed
CN-109776037-A A kind of high-strength waterproof concrete 湖南辰砾新材料有限公司 2019-05-21 CN disclosed
US-9133220-B2 Boron-containing 5-arylidene-3,5-dihydro-4H-imidazol-4-ones EVROGEN JOINT STOCK COMPANY (RU) 2015-09-15 US disclosed
US-20150177254-A1 Boron-Containing 5-arylidene-3,5-dihydro-4H-imidazol-4-ones EVROGEN JOINT STOCK COMPANY (RU) 2015-06-25 US disclosed
WO-2013078254-A1 BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2013-05-30 WO disclosed
US-20110263570-A1 PYRIMIDINE DERIVATIVES AS GPCR MODULATORS FOR USE IN THE TREATMENT OF OBESITY AND DIABETES SCHERING CORPORATION (US) 2011-10-27 US disclosed
US-20040092402-A1 Pyrimidine derivatives and herbicides containing the same SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2004-05-13 US disclosed
CN-1473155-A Pyrimidine derivatives and herbicides containing the same ס������ũҩ��ʽ���� 2004-02-04 CN disclosed
EP-1333029-A1 PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-08-06 EP disclosed
EP-0326389-B1 Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES (JP) 1996-09-11 EP disclosed
US-4935516-A Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES, LTD. (JP) 1990-06-19 US disclosed
EP-0326389-A2 Process for preparing 4-hydroxypyrimidine UBE INDUSTRIES, LTD. (JP) 1989-08-02 EP disclosed