Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921617 | 0.83 | ACACB (0.36) | ACACBMEN1KMT2ATNK2PSMB1 | |
| SCHEMBL24920648 | 0.79 | ACACB (0.46) | ACACBRAB9AMAPTPARP10LMNA | |
| SCHEMBL24920613 | 0.79 | ACACB (0.37) | ACACBMEN1KMT2APSMB1PSMB5 | |
| SCHEMBL24922351 | 0.73 | ACACB (0.38) | ACACBMEN1KMT2AKDM4EPOLB | |
| SCHEMBL30212445 | 0.72 | ACACB (0.37) | ACACBMEN1KMT2AMAPTPARP10 | |
| SCHEMBL24922311 | 0.71 | AR (0.35) | ACACBMEN1KMT2APSMB1PSMB5 | |
| SCHEMBL27234163 | 0.70 | RAB9A (0.35) | MEN1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL27234158 | 0.70 | RAB9A (0.35) | MEN1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL6135358 | 0.70 | NPY1R (0.47) | ACACBMEN1KMT2APSMB1PSMB5 | |
| SCHEMBL24920624 | 0.70 | ACACB (0.38) | ACACBKDM4EPOLBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |