Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921249 | 0.87 | ACACB (0.31) | ACACBSCN9APSMB1PSMB5PSMB2 | |
| SCHEMBL27233964 | 0.87 | ACACB (0.31) | ACACBSCN9APSMB1PSMB5PSMB2 | |
| SCHEMBL27233960 | 0.87 | ACACB (0.31) | ACACBSCN9APSMB1PSMB5PSMB2 | |
| SCHEMBL24922678 | 0.82 | NPBWR1 (0.37) | SCN9AHCRTR1HCRTR2LMNAHPGD | |
| SCHEMBL24921453 | 0.80 | CHRNB2 (0.39) | ACACBPARP10MAPTLMNATP53 | |
| SCHEMBL30212233 | 0.80 | CHRNB2 (0.39) | ACACBPARP10MAPTLMNATP53 | |
| SCHEMBL24921455 | 0.79 | ACACB (0.38) | ACACBSCN9A | |
| SCHEMBL24922693 | 0.79 | ACACB (0.35) | ACACBPSMB1PSMB5PSMB2PARP10 | |
| SCHEMBL24922619 | 0.76 | ACACB (0.40) | ACACBPARP10MAPTLMNATP53 | |
| SCHEMBL24921975 | 0.76 | ACACB (0.38) | ACACBPARP10MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |