Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868178 | 0.82 | — | — | |
| SCHEMBL24917922 | 0.82 | — | — | |
| SCHEMBL20715280 | 0.82 | — | — | |
| SCHEMBL16541852 | 0.77 | TRPV6 (0.40) | GBA1HDAC8HDAC6HDAC1 | |
| SCHEMBL14207963 | 0.75 | HDAC8 (0.46) | GBA1HDAC8HDAC6HDAC1 | |
| SCHEMBL9921271 | 0.75 | HDAC8 (0.46) | GBA1HDAC8HDAC6HDAC1 | |
| SCHEMBL14207962 | 0.75 | HDAC8 (0.46) | GBA1HDAC8HDAC6HDAC1 | |
| SCHEMBL20330340 | 0.74 | CHRNB4 (0.38) | CHRNA3CHRNB4 | |
| SCHEMBL25541248 | 0.73 | DRD2 (0.36) | GBA1HDAC8HDAC6HDAC1 | |
| SCHEMBL25542061 | 0.73 | DRD2 (0.36) | GBA1HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |