Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585298 | 0.86 | FFAR1 (0.51) | FFAR1FFAR4CYP1A2GRM5SIGMAR1 | |
| SCHEMBL30104886 | 0.84 | FFAR1 (0.48) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL7504948 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4GRM5SIGMAR1MAOB | |
| SCHEMBL24925945 | 0.83 | FFAR1 (0.47) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL37703522 | 0.83 | GRM5 (0.49) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL27508668 | 0.81 | FFAR1 (0.46) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL29187194 | 0.81 | GRM5 (0.54) | FFAR1FFAR4CYP1A2GRM5SIGMAR1 | |
| SCHEMBL16010836 | 0.81 | FFAR1 (0.55) | FFAR1FFAR4GRM5MAOB | |
| SCHEMBL28811665 | 0.79 | SIGMAR1 (0.48) | GRM5SIGMAR1MAOB | |
| SCHEMBL21163945 | 0.78 | FFAR1 (0.49) | FFAR1FFAR4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4124361-A1 | MACROCYCLIC LIGANDS WITH PICOLINATE GROUP(S), COMPLEXES THEREOF AND MEDICAL USES THEREOF | Guerbet (FR) | 2023-02-01 | — | — | EP | disclosed |