Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922969 | 0.83 | FFAR1 (0.50) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL28585298 | 0.82 | FFAR1 (0.51) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL30104886 | 0.80 | FFAR1 (0.48) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL7504948 | 0.80 | FFAR1 (0.61) | FFAR1FFAR4GRM5SIGMAR1MMP2 | |
| SCHEMBL37703522 | 0.79 | GRM5 (0.49) | FFAR1FFAR4GRM5SIGMAR1MMP2 | |
| SCHEMBL27508668 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL29187194 | 0.77 | GRM5 (0.54) | FFAR1FFAR4GRM5SIGMAR1 | |
| SCHEMBL16010836 | 0.77 | FFAR1 (0.55) | FFAR1FFAR4GRM5 | |
| SCHEMBL26868265 | 0.76 | PTGS2 (0.47) | — | |
| SCHEMBL21163945 | 0.75 | FFAR1 (0.49) | FFAR1FFAR4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006938-A1 | MACROCYCLIC LIGANDS WITH PICOLINATE GROUP(S), COMPLEXES AND MEDICAL USES THEREOF | GUERBET (FR) | 2023-02-02 | — | — | WO | disclosed |