SCHEMBL24923010

SCHEMBL24923010

CNCC(=O)NC(C)C=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.33
CTSS P25774 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26958829 0.84 ALDH1A1 (0.34)
SCHEMBL24270669 0.81 TSHR (0.35) ACACB
SCHEMBL22271666 0.81 LMNA (0.39)
SCHEMBL24366099 0.79 ACACB (0.32) ACACB
SCHEMBL11379505 0.77
SCHEMBL27340759 0.77
SCHEMBL8243268 0.77
SCHEMBL22030207 0.76 CAPN1 (0.40)
SCHEMBL18578916 0.76 CAPN1 (0.40)
SCHEMBL18054762 0.76 ALDH1A1 (0.39) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006084-A1 ANTI-DLL3 ANTIBODY AND PREPARATION METHOD THEREFOR, DRUG CONJUGATE AND APPLICATION THEREOF 上海复旦张江生物医药股份有限公司 2023-02-02 WO disclosed