SCHEMBL24923150

SCHEMBL24923150

c1cc(-c2cccc(-n3c4ccccc4c4c5c(ccc43)oc3ccccc35)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
PLA2G10 O15496 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPT P10636 2/20 0.33
HSD17B10 Q99714 2/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
WNK1 Q9H4A3 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889962 0.99 KDM4E (0.39) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24675445 0.95 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24676082 0.95 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24676318 0.95 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL18996090 0.94 ATM (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24676233 0.94 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24728736 0.94 PLA2G2A (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17246174 0.93 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL9889952 0.92 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL19652944 0.91 PLA2G2A (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A KDM4E 3096/4885ATM 2806/4885L3MBTL1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.