SCHEMBL24923581

SCHEMBL24923581

CCCC1OC2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CN)O1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 14/20 0.64
▸ PGR P06401 7/20 0.63
▸ LMNA P02545 3/20 0.63
▸ HIF1A Q16665 3/20 0.63
▸ AR P10275 2/20 0.63
▸ CYP3A4 P08684 1/20 0.63
▸ MAPT P10636 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.63
▸ TDP1 Q9NUW8 1/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ ESR1 P03372 2/20 0.60
▸ ALDH1A1 P00352 1/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23962476 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL20149344 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL20149283 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL23961911 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL20149346 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL24591928 1.00 NR3C1 (0.64) NR3C1PGRLMNAHIF1AAR
SCHEMBL26228034 0.94 NR3C1 (0.65) NR3C1PGRLMNAHIF1AAR
SCHEMBL21153648 0.93 NR3C1 (0.73) NR3C1PGRLMNAHIF1AAR
SCHEMBL21153780 0.93 NR3C1 (0.73) NR3C1PGRLMNAHIF1AAR
SCHEMBL10073752 0.93 NR3C1 (0.73) NR3C1PGRLMNAHIF1AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230035898-A1 CYCLODEXTRIN PROTEIN DRUG CONJUGATES REGENERON PHARMACEUTICALS, INC. 2023-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230035898-A1 CYCLODEXTRIN PROTEIN DRUG CONJUGATES SDCBP, DDOST, KRTCAP2 NR3C1 565/4885PGR 3767/4885LMNA 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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