SCHEMBL2492372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492907	0.89	KIF11 (0.70)	KIF11TAAR1KDM4EKCNN4MEN1
	SCHEMBL2490788	0.89	KIF11 (0.44)	KIF11TAAR1KCNN4IDO1TDP1
	SCHEMBL2493496	0.82	KIF11 (0.37)	KIF11KCNN4IDO1ALDH1A1TDP1
	SCHEMBL2489496	0.79	KIF11 (0.35)	KIF11KDM4EKCNN4MEN1ALDH1A1
	SCHEMBL2489578	0.79	KIF11 (0.56)	KIF11KCNN4ALOX15TSHRKCNE1
	SCHEMBL2490388	0.78	KIF11 (0.55)	KIF11TAAR1KDM4EMEN1TRPM2
	SCHEMBL2490799	0.76	KIF11 (0.52)	KIF11TAAR1KDM4EIDO1ALDH1A1
	SCHEMBL2491322	0.73	KIF11 (0.49)	KIF11KCNN4ALDH1A1ALOX15TSHR
	SCHEMBL2492363	0.72	KIF11 (1.00)	KIF11TAAR1KDM4EKCNN4MEN1
	SCHEMBL2492412	0.71	KIF11 (0.46)	KIF11KCNN4ALOX15TSHRKCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.