Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199498 | 0.89 | KIF11 (0.79) | KIF11SMN1; SMN2TK2TK1 | |
| SCHEMBL13671082 | 0.88 | KIF11 (0.78) | KIF11TAAR1SMN1; SMN2HRH4KDM4E | |
| SCHEMBL4454297 | 0.88 | KIF11 (0.78) | KIF11TAAR1SMN1; SMN2HRH4KDM4E | |
| SCHEMBL11913616 | 0.88 | KIF11 (0.78) | KIF11TAAR1SMN1; SMN2HRH4KDM4E | |
| SCHEMBL28661706 | 0.88 | KIF11 (0.78) | KIF11TAAR1SMN1; SMN2HRH4KDM4E | |
| SCHEMBL2494600 | 0.87 | KIF11 (0.77) | KIF11SMN1; SMN2HRH4DUTTK2 | |
| SCHEMBL2490823 | 0.86 | KIF11 (0.73) | KIF11SMN1; SMN2SLC6A1 | |
| SCHEMBL3617308 | 0.86 | KIF11 (0.73) | KIF11SMN1; SMN2SLC6A1 | |
| SCHEMBL11275984 | 0.85 | KIF11 (0.74) | KIF11TAAR1HRH4ALOX15TSHR | |
| SCHEMBL8703547 | 0.84 | KIF11 (0.71) | KIF11HRH4TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-11-19 | — | — | US | claimed |
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | claimed |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-12-11 | — | — | US | claimed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | claimed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | claimed |
| EP-4234042-B1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEM IND INC (JP) | 2025-08-13 | — | — | EP | disclosed |
| US-12358867-B1 | Peptoid-based inhibitors of the protein arginine methyltransferase (PRMT) family | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2025-07-15 | — | — | US | disclosed |
| US-11993556-B1 | Peptoid-based inhibitors of the protein arginine methyltransferase (PRMT) family | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4234042-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | Pola Chemical Industries, Inc. (JP) | 2023-08-30 | — | — | EP | disclosed |
| EP-3708148-B1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEM IND INC (JP) | 2023-07-19 | — | — | EP | disclosed |
| CN-112402279-A | Whitening cosmetic and use of composition containing D-panthenol in preparation of whitening cosmetic | 宝丽化成工业有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112402285-A | Whitening cosmetic and use of composition containing D-panthenol in preparation of whitening cosmetic | 宝丽化成工业有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-8846012-B2 | Melanin production inhibitor | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| US-4438260-A | Sisomicin compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0056575-A1 | Sisomicin derivatives, process for their preparation and their use as pharmaceutical compositions | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358867-B1 | Peptoid-based inhibitors of the protein arginine methyltransferase (PRMT) family | PRMT1, PRMT3, PRMT5 | KIF11 3606/4885TAAR1 4223/4885SMN1; SMN2 3387/4885 |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, TH | KIF11 4556/4885TAAR1 225/4885SMN1; SMN2 3632/4885 |
| US-11993556-B1 | Peptoid-based inhibitors of the protein arginine methyltransferase (PRMT) family | PRMT1, PRMT3, PRMT5 | KIF11 3606/4885TAAR1 4223/4885SMN1; SMN2 3387/4885 |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | TYR, MC1R, F12 | KIF11 4605/4885TAAR1 194/4885SMN1; SMN2 3663/4885 |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, MC1R | KIF11 4611/4885TAAR1 225/4885SMN1; SMN2 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.