Ether

Ether

SCHEMBL2492476

C=CC(=O)OCCCOC(=O)C=C.CCOCC.OCCO

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.63
HPGD P15428 1/20 0.63
ALDH1A1 P00352 7/20 0.59
CYP3A4 P08684 2/20 0.59
TP53 P04637 3/20 0.53
HIF1A Q16665 3/20 0.53
HSD17B10 Q99714 1/20 0.53
THRB P10828 3/20 0.49
ATM Q13315 1/20 0.42
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HCAR2 Q8TDS4 3/20 0.38
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL22282995 0.96 TSHR (0.64) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL1088054 0.92 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL2869629 0.91 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL20572982 0.91 TSHR (0.73) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL9632670 0.90 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL9406512 0.89 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL2120616 0.89 TSHR (0.76) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL237172 0.89 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4TP53
Ethylene Glycol SCHEMBL2059776 0.88 TSHR (0.74) TSHRHPGDALDH1A1CYP3A4TP53
Ether SCHEMBL15941530 0.87 TSHR (0.85) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362291-B2 poly-1,3-propylene glycol mono or di-(meth)acrylates in combination with a polymerization inhibitor; for coatings and radiation curable applications; desired physical properties and reduced degradation during production; 1,3-propanediol can be a renewable monomer E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-29 US disclosed
EP-2370500-B1 ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL DU PONT (US) 2012-09-05 EP disclosed
US-8207372-B2 Process for the production of acrylic and methacrylic esters of poly(trimethylene ether) glycol E I DU PONT DE NEMOURS AND COMPANY (US) 2012-06-26 US disclosed
US-8198360-B2 (Meth)acrylic esters of poly(trimethylene ether) glycol and uses thereof E I DU PONT DE NEMOURS AND COMPANY (US) 2012-06-12 US disclosed
EP-2370500-A1 ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
EP-2370499-A1 PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
EP-2370483-A1 (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
WO-2010074805-A1 PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010074806-A1 (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010074803-A1 ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
US-20100160672-A1 PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
US-20100159767-A1 (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
US-20100160538-A1 ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160672-A1 PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL MMAB, PARG, PAM TSHR 2933/4885HPGD 277/4885ALDH1A1 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.