Ether

Ether

SCHEMBL9406512

C=CC(=O)OCCC.CCOCC.OCCO

nearest known ligand 0.59

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.59
HPGD P15428 1/20 0.58
ALDH1A1 P00352 7/20 0.53
TP53 P04637 3/20 0.53
HIF1A Q16665 3/20 0.53
HSD17B10 Q99714 1/20 0.53
THRB P10828 4/20 0.49
CYP3A4 P08684 2/20 0.48
HCAR2 Q8TDS4 3/20 0.44
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ATM Q13315 1/20 0.38
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL1088054 0.92 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
Ethylene Glycol SCHEMBL27646440 0.92 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Ether SCHEMBL2492476 0.89 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
Ether SCHEMBL22282995 0.89 TSHR (0.64) TSHRHPGDALDH1A1TP53HIF1A
Ether SCHEMBL2120616 0.89 TSHR (0.76) TSHRHPGDALDH1A1TP53HIF1A
Ether SCHEMBL2869629 0.88 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Ether SCHEMBL20572982 0.88 TSHR (0.73) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL3766624 0.87 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL5575370 0.86 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9488445 0.86 TSHR (0.79) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292965-A Monomethoxy propoxylated glycerol DIAMOND SHAMROCK CHEMICALS COMPANY 1994-03-08 US disclosed
US-5243085-A Starting materials for improved radiation hardenable diluents DIAMOND SHAMROCK CHEMICAL CO. (US) 1993-09-07 US disclosed
US-5159119-A Monomethyl ether of trans 1,4-cyclohexanedimethylol DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1992-10-27 US disclosed
EP-0222059-B1 IMPROVED RADIATION-HARDENABLE DILUENTS HENKEL CORPORATION (a Delaware corp.) (US) 1992-07-08 EP disclosed
US-5110889-A Lower alkyl ether acrylates of polyols; coatings DIAMOND SHAMROCK CHEMICAL CO. (US) 1992-05-05 US disclosed
US-5053554-A Monomethyl ether of an ethoxylated or propoxylated(2 average) neopentyl glycol; nonvolatile coating formulation; fact cure; low viscosity; shrinkage inhibition; rheology DIAMOND SHAMROCK CHEMICAL COMPANY 1991-10-01 US disclosed
US-4876384-A ALKYL ETHER ACRYLATES AND METHACRYLATES OF ALKOXYLATED AND NONALKOXYLATED POLYOLS; LOW VISCOSITY; SHRINKAGE INHIBITION DIAMOND SHAMROCK CHEMICALS CO. (US) 1989-10-24 US disclosed
EP-0222059-A2 Improved radiation-hardenable diluents HENKEL CORPORATION (a Delaware corp.) (US) 1987-05-20 EP disclosed