Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL6686130 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Tetrahydrofuran SCHEMBL2311865 | 0.92 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Cyclopropane SCHEMBL11750295 | 0.90 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL660331 | 0.90 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21630258 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL30363554 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14875 | 0.87 | — | — | |
| Ethylene SCHEMBL8850416 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene Glycol SCHEMBL8650028 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2457464 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207372-B2 | Process for the production of acrylic and methacrylic esters of poly(trimethylene ether) glycol | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-26 | — | — | US | claimed |
| US-20100160672-A1 | PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | claimed |
| US-8362291-B2 | poly-1,3-propylene glycol mono or di-(meth)acrylates in combination with a polymerization inhibitor; for coatings and radiation curable applications; desired physical properties and reduced degradation during production; 1,3-propanediol can be a renewable monomer | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2370500-B1 | ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | DU PONT (US) | 2012-09-05 | — | — | EP | disclosed |
| US-8207372-B2 | Process for the production of acrylic and methacrylic esters of poly(trimethylene ether) glycol | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-26 | — | — | US | disclosed |
| US-8198360-B2 | (Meth)acrylic esters of poly(trimethylene ether) glycol and uses thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-12 | — | — | US | disclosed |
| EP-2370499-A1 | PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. du Pont de Nemours and Company (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2370483-A1 | (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF | E. I. du Pont de Nemours and Company (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2370500-A1 | ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. du Pont de Nemours and Company (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010074805-A1 | PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074806-A1 | (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074803-A1 | ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100160538-A1 | ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160672-A1 | PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100159767-A1 | (METH)ACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL AND USES THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160672-A1 | PROCESS FOR THE PRODUCTION OF ACRYLIC AND METHACRYLIC ESTERS OF POLY(TRIMETHYLENE ETHER) GLYCOL | MMAB, PARG, PAM | TSHR 2933/4885ALDH1A1 815/4885TP53 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.