SCHEMBL2492488

SCHEMBL2492488

Cc1ccc(NC(=O)C(=O)Cc2nc3ccccc3o2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 2/20 0.53
PTPN1 P18031 2/20 0.53
MAPT P10636 5/20 0.51
USP2 O75604 1/20 0.51
P2RY14 Q15391 2/20 0.48
RAB9A P51151 7/20 0.48
NPC1 O15118 6/20 0.48
TP53 P04637 3/20 0.46
PTPN5 P54829 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
KDM4E B2RXH2 1/20 0.45
RXFP1 Q9HBX9 2/20 0.45
STAT1 P42224 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491756 0.77 MAPT (0.49) MAPTRAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL11835830 0.77 MEN1 (0.61) MAPTP2RY14RAB9ANPC1TP53
SCHEMBL30619952 0.75 MAPT (0.53) PTPN2PTPN1MAPTUSP2RAB9A
SCHEMBL28544876 0.75 MAPT (0.53) PTPN2PTPN1MAPTUSP2RAB9A
SCHEMBL18851542 0.75 MAPT (0.63) MAPTUSP2RAB9ANPC1TP53
SCHEMBL5624696 0.74 MAPT (0.54) MAPTUSP2RAB9ANPC1TP53
SCHEMBL14310604 0.74 RAB9A (0.54) MAPTRAB9ANPC1TP53SMN1; SMN2
SCHEMBL11468565 0.74 RAB9A (0.54) MAPTRAB9ANPC1TP53SMN1; SMN2
SCHEMBL27139465 0.73 RAB9A (0.58) MAPTRAB9ANPC1TP53SMN1; SMN2
SCHEMBL13101605 0.73 RAB9A (0.50) MAPTP2RY14RAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed