Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544876 | 1.00 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28688484 | 0.85 | BCHE (0.54) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28688356 | 0.85 | NPC1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28668490 | 0.84 | KMT2A (0.55) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7336243 | 0.77 | MAPT (0.63) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28692097 | 0.77 | ALDH1A1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL31265500 | 0.76 | SMN1; SMN2 (0.83) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28665946 | 0.75 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28681813 | 0.75 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2492488 | 0.75 | PTPN2 (0.53) | MAPTNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321526-B | Method for synthesizing heteroaromatic methylamine compound through redox-decarboxylation coupling reaction | 西北师范大学 | 2023-09-22 | — | — | CN | claimed |
| CN-112321526-B | Method for synthesizing heteroaromatic methylamine compound through redox-decarboxylation coupling reaction | 西北师范大学 | 2023-09-22 | — | — | CN | disclosed |