Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858277 | 0.93 | TSHR (0.47) | TSHRCES2FAAHCA12CA1 | |
| SCHEMBL24925061 | 0.88 | TSHR (0.43) | TSHRCES2FAAHCES1MEN1 | |
| SCHEMBL24925063 | 0.85 | — | — | |
| SCHEMBL24925065 | 0.83 | TSHR (0.36) | ALDH1A1TSHRCES2 | |
| SCHEMBL24924890 | 0.80 | — | — | |
| SCHEMBL15925689 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDATMCA12 | |
| SCHEMBL221345 | 0.75 | TSHR (0.52) | ALDH1A1TSHRHPGDATMCES2 | |
| SCHEMBL23003301 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDATMCES2 | |
| SCHEMBL24924895 | 0.73 | CYP3A4 (0.50) | ALDH1A1TSHRATMCA1CA2 | |
| SCHEMBL196154 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDATMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007465-A1 | FLUORINATED ETHERS, THERMAL MANAGEMENT FLUIDS, AND METHODS AND APPARATUSES USING THEM | CASTROL LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |