SCHEMBL24924896

SCHEMBL24924896

CCCCOC(C)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
DNM1 Q05193 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20443588 0.91 DNM1 (0.45) DNM1CES2CES1TSHR
SCHEMBL24925059 0.89 TSHR (0.41) ADRB2ADRB1ADRB3SMN1; SMN2CES2
SCHEMBL24925064 0.87
SCHEMBL24925058 0.85 DNM1 (0.32) DNM1
SCHEMBL17922079 0.85 HSD17B10 (0.32)
SCHEMBL24924897 0.84
SCHEMBL26078103 0.84 DNM1 (0.33) ADRB2ADRB1ADRB3DNM1SMN1; SMN2
SCHEMBL12123287 0.80 HTR1B (0.33)
SCHEMBL798901 0.79
SCHEMBL13898471 0.78 ADRB2 (0.36) ADRB2ADRB1ADRB3DNM1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007465-A1 FLUORINATED ETHERS, THERMAL MANAGEMENT FLUIDS, AND METHODS AND APPARATUSES USING THEM CASTROL LIMITED (GB) 2023-02-02 WO disclosed