Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490235 | 0.94 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL2489689 | 0.88 | PTGDR2 (0.62) | PTGDR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2492872 | 0.83 | PTGDR2 (0.50) | PTGDR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2130246 | 0.83 | PTGDR2 (0.71) | PTGDR2 | |
| SCHEMBL2489821 | 0.82 | PTGDR2 (0.69) | PTGDR2NPC1RAB9A | |
| SCHEMBL2489986 | 0.82 | PTGDR2 (0.53) | PTGDR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2489819 | 0.81 | PTGDR2 (0.50) | PTGDR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2131591 | 0.81 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL17818011 | 0.81 | PTGDR2 (0.57) | PTGDR2 | |
| SCHEMBL2492752 | 0.81 | PTGDR2 (0.56) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |