SCHEMBL24924947

SCHEMBL24924947

c1nnc(-c2cnns2)o1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 13/20 0.41
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
HTT P42858 3/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 2/20 0.40
RUNX1 Q01196 2/20 0.40
CBFB Q13951 2/20 0.40
GFER P55789 1/20 0.40
TSHR P16473 1/20 0.35
TLR8 Q9NR97 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12906161 0.71 NOTUM (0.59) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL22015413 0.69 HPGDS (0.37) MAPTALDH1A1HTTGAAHPGD
SCHEMBL262142 0.65 KDM4E (0.49) NOTUMMAPTALDH1A1GAAHPGD
SCHEMBL22738890 0.65 NOTUM (0.48) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL7255351 0.64 NOTUM (0.38) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL20016442 0.64 NOTUM (0.42) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL3412890 0.64 NOTUM (0.42) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL17694561 0.62 NOTUM (0.78) NOTUMMAPTALDH1A1HTTHPGD
SCHEMBL539177 0.62 NOTUM (0.41) NOTUMALDH1A1HPGDTSHRLMNA
SCHEMBL5959922 0.61 NOTUM (0.39) NOTUMMAPTALDH1A1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230015063-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS UNIV ARIZONA STATE (US) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230015063-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP NOTUM 2731/4885MAPT 839/4885ALDH1A1 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.