Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 14/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12906161 | 0.68 | NOTUM (0.59) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL24924947 | 0.64 | NOTUM (0.41) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL27883020 | 0.61 | NOTUM (0.44) | NOTUMTSHRMAPTALDH1A1KDM4E | |
| SCHEMBL2469949 | 0.61 | NOTUM (0.38) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL16799432 | 0.61 | NOTUM (0.42) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL17694561 | 0.60 | NOTUM (0.78) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL539177 | 0.60 | NOTUM (0.41) | NOTUMTSHRALDH1A1LMNAHPGD | |
| SCHEMBL4760927 | 0.59 | NOTUM (0.39) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL2610163 | 0.58 | NOTUM (0.75) | NOTUMTSHRMAPTALDH1A1TLR8 | |
| SCHEMBL28450882 | 0.58 | NOTUM (0.38) | NOTUMTSHRMAPTTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070712-A1 | THIOIBOTENIC ACID AND DERIVATIVES THEREOF | H. LUNDBECK A/S (DK) | 2003-08-28 | — | — | WO | disclosed |