⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253539 | 0.90 | — | — | |
| SCHEMBL24253557 | 0.76 | GABRA1 (0.35) | — | |
| SCHEMBL25892465 | 0.71 | PCSK9 (0.30) | — | |
| SCHEMBL24253460 | 0.71 | PCSK9 (0.32) | — | |
| SCHEMBL15423532 | 0.67 | DYRK1A (0.32) | — | |
| SCHEMBL24874280 | 0.61 | — | — | |
| SCHEMBL17132597 | 0.59 | CYP1A2 (0.33) | — | |
| SCHEMBL19545388 | 0.58 | PCSK9 (0.33) | — | |
| SCHEMBL24253457 | 0.58 | GABRA1 (0.35) | — | |
| SCHEMBL25064747 | 0.58 | PRKAB2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027684-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |