Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798116 | 0.96 | TDP1 (0.54) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 | |
| SCHEMBL14524266 | 0.89 | TDP1 (0.64) | TDP1L3MBTL1CHRNA7CYP2A6HRH4 | |
| SCHEMBL22161582 | 0.87 | L3MBTL1 (0.61) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 | |
| SCHEMBL23014817 | 0.86 | TDP1 (0.65) | TDP1L3MBTL1CHRNA7CYP2A6HRH4 | |
| SCHEMBL4812510 | 0.81 | CHRNA7 (0.53) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 | |
| SCHEMBL273379 | 0.81 | CHRNA7 (0.57) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 | |
| SCHEMBL774717 | 0.81 | CHRNB2 (0.52) | TDP1L3MBTL1CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL2608908 | 0.81 | CHRNA7 (0.49) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 | |
| SCHEMBL30935631 | 0.80 | CHRNA7 (0.52) | TDP1L3MBTL1CHRNA7CYP2A6HRH1 | |
| SCHEMBL9755554 | 0.80 | CHRNA7 (0.52) | TDP1L3MBTL1CHRNA7CYP2A6CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106904710-A | A kind of flocculant spiral pipeline, preparation method and applications | 徐州工程学院 | 2017-06-30 | — | — | CN | claimed |
| US-11702429-B2 | mTORC modulators and uses thereof | AEOVIAN PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230013344-A1 | MTORC MODULATORS AND USES THEREOF | EVOTEC (FRANCE) SAS (FR) | 2023-01-19 | — | — | US | disclosed |
| CN-106904710-A | A kind of flocculant spiral pipeline, preparation method and applications | 徐州工程学院 | 2017-06-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702429-B2 | mTORC modulators and uses thereof | MTOR, RICTOR, RPTOR | TDP1 3445/4885L3MBTL1 1721/4885CHRNA7 4861/4885 |
| US-20230013344-A1 | MTORC MODULATORS AND USES THEREOF | MTOR, RICTOR, RPTOR | TDP1 3445/4885L3MBTL1 1721/4885CHRNA7 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.