Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.61 |
| ▸ | OXTR | P30559 | 2/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660180 | 0.95 | NOTUM (0.69) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| SCHEMBL29520673 | 0.95 | NOTUM (0.69) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL29520826 | 0.94 | NOTUM (0.67) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL29521106 | 0.94 | NOTUM (0.67) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| SCHEMBL5006023 | 0.89 | TSHR (0.75) | ALDH1A1TSHRMAPK1NOTUMPOLB | |
| SCHEMBL5398751 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TSHRNOTUMKDM4EPOLB | |
| SCHEMBL9559719 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRNOTUMKDM4EPOLB | |
| SCHEMBL25937310 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRNOTUMKDM4EPOLB | |
| SCHEMBL25430987 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRNOTUMKDM4EPOLB | |
| SCHEMBL29522633 | 0.83 | TSHR (0.67) | ALDH1A1TSHRMAPK1NOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | ALDH1A1 1598/4885TSHR 1190/4885LMNA 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.