⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905316 | 0.59 | — | — | |
| SCHEMBL23469127 | 0.58 | POLB (0.31) | — | |
| SCHEMBL3916283 | 0.57 | — | — | |
| SCHEMBL3328286 | 0.56 | — | — | |
| SCHEMBL31521725 | 0.55 | RAB9A (0.44) | — | |
| SCHEMBL7846286 | 0.53 | GABRP (0.42) | — | |
| SCHEMBL1018547 | 0.53 | PARP1 (0.42) | — | |
| SCHEMBL7542992 | 0.52 | CYP1A2 (0.43) | — | |
| Propionamide SCHEMBL25289008 | 0.51 | — | — | |
| Propionamide SCHEMBL28211176 | 0.51 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003002-A1 | ANNULATED PYRIDAZINE COMPOUND | アステラス製薬株式会社 | 2023-01-26 | — | — | WO | disclosed |