Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24927648 | 0.81 | SLC6A9 (0.32) | SLC6A9 | |
| SCHEMBL22541496 | 0.81 | SLC6A9 (0.34) | SLC6A9 | |
| SCHEMBL24926315 | 0.81 | SLC6A9 (0.34) | SLC6A9 | |
| SCHEMBL15471354 | 0.79 | GBA1 (0.38) | — | |
| SCHEMBL18199654 | 0.79 | GBA1 (0.38) | — | |
| SCHEMBL24926332 | 0.79 | GBA1 (0.38) | — | |
| SCHEMBL15471139 | 0.78 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL24926280 | 0.77 | HTT (0.37) | SLC6A9 | |
| SCHEMBL15934174 | 0.77 | HRH3 (0.45) | HSD11B1 | |
| SCHEMBL24926283 | 0.76 | GBA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230031954-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | TETRAPHASE PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230031954-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | MCL1, ABL1, MALT1 | HSD11B1 3617/4885SLC6A9 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.