SCHEMBL2492685

SCHEMBL2492685

C(#Cc1c2ccccc2c(-c2ccccc2)c2ccccc12)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
MAPT P10636 4/20 0.40
ACHE P22303 2/20 0.39
ADORA2A P29274 1/20 0.38
CYP1A2 P05177 3/20 0.38
GRM5 P41594 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30394466 1.00 APP (0.50) APPL3MBTL1TDP1ATMMAPT
SCHEMBL5955989 0.92 CYP1A1 (0.48) APPL3MBTL1TDP1ATMMAPT
SCHEMBL1155420 0.88 ESR1 (0.46) APPL3MBTL1TDP1ATMMAPT
SCHEMBL55761 0.87 APP (0.67) APPL3MBTL1TDP1ATMMAPT
SCHEMBL29357652 0.87 APP (0.67) APPL3MBTL1TDP1ATMMAPT
SCHEMBL5955971 0.86 GRM5 (0.42) APPL3MBTL1TDP1ATMACHE
SCHEMBL5955125 0.85 APP (0.43) APPL3MBTL1TDP1ATMMAPT
SCHEMBL5955970 0.83 RARB (0.45) APPL3MBTL1TDP1ATMACHE
SCHEMBL7196394 0.82 APP (0.60) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL14565323 0.81 TSHR (0.45) ATMMEN1ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351580-B2 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-16 US claimed
US-20180258111-A1 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-09-13 US claimed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US claimed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US claimed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US claimed
US-20060141287-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-06-29 US claimed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US claimed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US claimed
US-10351580-B2 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-16 US disclosed
US-20180258111-A1 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-09-13 US disclosed
JP-2011213596-A 9-(4-AMINOPHENYL)-10-(4-AMINOPHENYLETHYNYL)ANTHRACENE, AND METHOD FOR PRODUCING THE SAME WAKAYAMA SEIKA KOGYO KK 2011-10-27 JP disclosed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20060141287-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-06-29 US disclosed
US-20060040131-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-02-23 US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
WO-2005040303-A1 AGGREGATE ORGANIC LIGHT EMITTING DIODE DEVICES EASTMAN KODAK COMPANY (US) 2005-05-06 WO disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180258111-A1 Acene-based transmitter molecules for photon upconversion ACE, ACE2, AGTR1 APP 65/4885L3MBTL1 2867/4885TDP1 1526/4885
US-10351580-B2 Acene-based transmitter molecules for photon upconversion ACE, ACE2, AGTR1 APP 65/4885L3MBTL1 2867/4885TDP1 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.