SCHEMBL7196394

SCHEMBL7196394

C(#Cc1c(-c2ccccc2)c(C#Cc2ccccc2)c(-c2ccccc2)c(C#Cc2ccccc2)c1-c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.60
MAPT P10636 3/20 0.46
CYP1A2 P05177 3/20 0.43
GRM5 P41594 1/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KCNH2 Q12809 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861764 0.95 APP (0.55) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL4196157 0.93 APP (0.57) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL2492685 0.82 APP (0.50) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL30394466 0.82 APP (0.50) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL25383897 0.82 MAPT (0.50) APPMAPTCYP1A2GRM5CYP1A1
Diphenylacetylene SCHEMBL21271527 0.81 APP (0.80) APPMAPTCYP1A2GRM5CYP1A1
SCHEMBL3796509 0.81 APP (0.80) APPMAPTCYP1A2GRM5CYP3A4
Diphenylacetylene SCHEMBL27926128 0.81 APP (0.80) APPMAPTCYP1A2GRM5CYP1A1
Diphenylacetylene SCHEMBL960609 0.78 APP (1.00) APPMAPTCYP1A2GRM5CYP3A4
Diphenylacetylene SCHEMBL29188592 0.78 APP (1.00) APPMAPTCYP1A2GRM5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6646081-B2 Useful in making low dielectric constant insulating layers in microelectronic devices DOW GLOBAL TECHNOLOGIES INC. 2003-11-11 US claimed
EP-1244724-A1 POLYARYLENE COMPOSITIONS WITH ENHANCED MODULUS PROFILES Dow Global Technologies, Inc. (US) 2002-10-02 EP claimed
WO-2001038417-A1 POLYARYLENE COMPOSITIONS WITH ENHANCED MODULUS PROFILES DOW GLOBAL TECHNOLOGIES INC. (US) 2001-05-31 WO claimed
US-4097460-A DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS HERCULES INCORPORATED (US) 1978-06-27 US claimed
US-4070333-A AROMATIZATION CATALYST, ADDITION POLYMERIZATION HERCULES INCORPORATED (US) 1978-01-24 US claimed
WO-1991009066-A1 HIGH CARBON RESINS AND FOAMS HYPERION CATALYSIS INTERNATIONAL, INC. (US) 1991-06-27 WO disclosed
US-4690962-A BLEND OF ACETYLENIC OLIGOMER WITH PLASTICIZER AND TOUGHNESS AGENTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1987-09-01 US disclosed
US-4592944-A Integrated circuit chip sealed with a protective coating INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1986-06-03 US disclosed
EP-0095048-A2 Oligomer coated electronic circuit component and method of coating International Business Machines Corporation (US) 1983-11-30 EP disclosed
EP-0000385-B1 THERMOSETTING COMPOSITIONS BASED ON POLYARYLACETYLENES AND SUBSTITUTED POLYPHENYLENE OXIDES AND RESINS OBTAINED BY CURING THEM HERCULES INCORPORATED (US) 1981-08-26 EP disclosed
US-4144218-A MOLDING MATERIALS HERCULES INCORPORATED (US) 1979-03-13 US disclosed
EP-0000385-A1 Thermosetting compositions based on polyarylacetylenes and substituted polyphenylene oxides and resins obtained by curing them HERCULES INCORPORATED (US) 1979-01-24 EP disclosed
US-4097460-A DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS HERCULES INCORPORATED (US) 1978-06-27 US disclosed
US-4070333-A AROMATIZATION CATALYST, ADDITION POLYMERIZATION HERCULES INCORPORATED (US) 1978-01-24 US disclosed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026860-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-3993711-A THERMOSETTING RESINS; COUPLING AGENTS; CARBOXYLATED PREPOLYMER HERCULES INCORPORATED (US) 1976-11-23 US disclosed
US-3931093-A CURING HERCULES INCORPORATED (US) 1976-01-06 US disclosed