SCHEMBL2492697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL247849	0.93	MAPT (0.67)	MAPTLMNAKDM4EALDH1A1HSD17B10
	Hydrochloric Acid SCHEMBL2863287	0.90	MAPT (0.64)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL7012895	0.90	LMNA (0.56)	MAPTLMNATP53HTTMEN1
	SCHEMBL11544937	0.90	LMNA (0.56)	MAPTLMNATP53HTTMEN1
	SCHEMBL17278975	0.88	ADRA2A (0.49)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL19229357	0.85	MAPT (0.48)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL2492357	0.82	MAPT (0.67)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL526383	0.82	MAPT (0.58)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL21422614	0.81	NPC1 (0.41)	MAPTLMNAKDM4EALDH1A1HSD17B10
	SCHEMBL22156281	0.81	LMNA (0.64)	MAPTLMNAALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.