Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 4/20 | 0.35 |
| ▸ | ADH1C | P00326 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283512 | 0.80 | HRH3 (0.42) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL9283576 | 0.78 | HRH3 (0.39) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL15387169 | 0.77 | HRH3 (0.40) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL20096008 | 0.77 | HRH4 (0.40) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL18523207 | 0.75 | ADH1C (0.35) | ADH1AADH1CKDM4EALDH1A1CYP2D6 | |
| SCHEMBL9283514 | 0.75 | HRH4 (0.36) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL12065407 | 0.74 | HRH3 (0.41) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL170201 | 0.72 | ADH1A (0.48) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL20197642 | 0.72 | ADH1A (0.48) | HRH3HRH4ADH1AADH1CKDM4E | |
| SCHEMBL21180049 | 0.72 | ADH1A (0.48) | HRH3HRH4ADH1AADH1CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230031954-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | TETRAPHASE PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230031954-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | MCL1, ABL1, MALT1 | HRH3 2940/4885HRH4 2677/4885ADH1A 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.