Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23355464 | 0.91 | STIM1 (0.38) | ADORA2AADORA1WNT1GSK3BDYRK1A | |
| SCHEMBL19707871 | 0.85 | HDAC3 (0.43) | KEAP1NFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL23355424 | 0.85 | KEAP1 (0.35) | KEAP1NFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL23355385 | 0.79 | GSK3B (0.42) | WNT1GSK3BDYRK1AHDAC3HDAC4 | |
| SCHEMBL23019011 | 0.78 | HDAC3 (0.41) | KEAP1NFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL21612766 | 0.78 | HDAC3 (0.35) | WNT1GSK3BDYRK1AKEAP1NFE2L2 | |
| SCHEMBL28522620 | 0.76 | STIM1 (0.37) | WNT1GSK3BDYRK1AHDAC3HDAC4 | |
| SCHEMBL19454746 | 0.76 | CHRNB2 (0.53) | DYRK1AKEAP1NFE2L2HDAC3HDAC4 | |
| SCHEMBL23355465 | 0.75 | GSK3B (0.37) | WNT1GSK3BDYRK1AHDAC3HDAC4 | |
| SCHEMBL24926744 | 0.75 | CYP17A1 (0.41) | WNT1GSK3BDYRK1AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025510-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025510-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVES | ERBB2, EGFR, ERBB3 | ADORA2A 3811/4885ADORA1 3455/4885WNT1 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.