Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008113 | 0.90 | CYP1A2 (0.48) | POLBRPA1CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6381168 | 0.88 | CYP1A2 (0.44) | POLBRPA1CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15009288 | 0.75 | CDC7 (0.54) | POLBRPA1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23980136 | 0.75 | POLB (0.52) | POLBRPA1CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31696438 | 0.72 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL19044281 | 0.71 | CYP1A2 (0.49) | POLBCYP1A2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1423019 | 0.69 | HTR2A (0.40) | — | |
| SCHEMBL1423651 | 0.68 | HTR2A (0.44) | — | |
| SCHEMBL6381453 | 0.67 | ALDH1A1 (0.42) | CYP1A2SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL28517075 | 0.67 | HTR2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |