Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22628861 | 0.77 | ADRA1A (0.54) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL3452953 | 0.76 | ADRA1A (0.53) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL6851022 | 0.75 | ADRA1A (0.53) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6852908 | 0.74 | ADRA1A (0.51) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL7332682 | 0.74 | HTR3A (0.50) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL12384814 | 0.73 | ADRA1A (0.50) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL13109150 | 0.73 | ADRA1A (0.50) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL4417884 | 0.73 | ADRA1A (0.50) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL9049065 | 0.73 | HTR3A (0.49) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL6850934 | 0.72 | HTR3A (0.48) | ADRA1AADRA1DHTR3AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |