Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3621160 | 0.94 | LOXL2 (0.47) | LOXL2DDAH1ADRA2CNPC1RAB9A | |
| SCHEMBL6468700 | 0.84 | LOXL2 (0.49) | LOXL2DDAH1ADRA2CNPC1RAB9A | |
| SCHEMBL6206770 | 0.83 | MAPT (0.48) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL6630971 | 0.82 | HDAC3 (0.47) | LOXL2NPC1RAB9AMAPTTP53 | |
| SCHEMBL14562892 | 0.81 | HSF1 (0.44) | LOXL2NPC1RAB9AMAPTTP53 | |
| SCHEMBL5703678 | 0.79 | HDAC3 (0.50) | LOXL2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6207598 | 0.79 | HDAC3 (0.50) | LOXL2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6462282 | 0.78 | NPC1 (0.38) | LOXL2DDAH1ADRA2CNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7255759 | 0.78 | HDAC3 (0.49) | LOXL2NPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7255756 | 0.78 | HDAC3 (0.49) | LOXL2NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122499-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2023-01-25 | — | — | EP | disclosed |