Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 18/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578049 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRHSD17B10SCN9A | |
| SCHEMBL8583881 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDTSHRHSD17B10SCN9A | |
| SCHEMBL8581988 | 0.83 | SCN9A (0.42) | ALDH1A1HPGDTSHRHSD17B10SCN9A | |
| SCHEMBL8585515 | 0.82 | SCN9A (0.43) | ALDH1A1HPGDTSHRHSD17B10SCN9A | |
| SCHEMBL15464809 | 0.81 | PKM (0.42) | ALDH1A1HPGDTSHRHSD17B10PKM | |
| SCHEMBL24928666 | 0.80 | KDM4E (0.41) | ALDH1A1HPGDTSHRHSD17B10SCN9A | |
| SCHEMBL29835245 | 0.78 | PKM (0.47) | ALDH1A1HPGDTSHRHSD17B10PKM | |
| SCHEMBL21865574 | 0.78 | PKM (0.47) | ALDH1A1HPGDTSHRHSD17B10PKM | |
| SCHEMBL29991315 | 0.77 | SOS1 (0.40) | ALDH1A1HPGDTSHRHSD17B10PKM | |
| SCHEMBL16759241 | 0.77 | TSHR (0.41) | ALDH1A1HPGDTSHRHSD17B10SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881657-A | Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators | 格雷沃尔夫治疗有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023007188-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2023-02-02 | — | — | WO | disclosed |