SCHEMBL24928675

SCHEMBL24928675

Cc1oncc1-c1cc(N)c(OC2CC(F)(F)C2)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929574 0.85 CSNK2A1 (0.36) BRD4
SCHEMBL24928858 0.85 CSNK2A1 (0.33) BRD4
SCHEMBL24929568 0.73 BRD4 (0.33) BRD4
SCHEMBL24928930 0.71
SCHEMBL30845580 0.71 POLB (0.33)
SCHEMBL24928671 0.71 POLB (0.33)
SCHEMBL24928672 0.68
SCHEMBL23850721 0.65 ALDH1A1 (0.40)
SCHEMBL22636625 0.64 ALDH1A1 (0.36)
SCHEMBL24930072 0.64 BRD4 (0.46) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376955-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2024-06-05 EP disclosed
CN-117881657-A Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators 格雷沃尔夫治疗有限公司 2024-04-12 CN disclosed
WO-2023007188-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2023-02-02 WO disclosed
WO-2023007188-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2023-02-02 WO disclosed