Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24928858 | 0.98 | CSNK2A1 (0.33) | CSNK2A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24929568 | 0.85 | BRD4 (0.33) | BRD4TDO2PDGFRBPDGFRAADRA1A | |
| SCHEMBL24928675 | 0.85 | BRD4 (0.31) | BRD4 | |
| SCHEMBL24930072 | 0.79 | BRD4 (0.46) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL23850721 | 0.70 | ALDH1A1 (0.40) | LMNAMAPTKMT2AL3MBTL1 | |
| SCHEMBL24930069 | 0.69 | CSNK2A1 (0.39) | CSNK2A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31198500 | 0.69 | ACLY (0.38) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL27675181 | 0.67 | GAA (0.62) | CSNK2A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22636625 | 0.67 | ALDH1A1 (0.36) | TDO2LMNAMAPTKMT2AL3MBTL1 | |
| SCHEMBL24928863 | 0.67 | CSNK2A1 (0.36) | CSNK2A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881657-A | Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators | 格雷沃尔夫治疗有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023007188-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2023-02-02 | — | — | WO | disclosed |