Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PEPD | P12955 | 2/20 | 0.35 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913400 | 0.94 | POLB (0.46) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL2913398 | 0.94 | POLB (0.46) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL6193034 | 0.93 | SMN1; SMN2 (0.42) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL24434718 | 0.91 | POLB (0.44) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL15193817 | 0.87 | SMN1; SMN2 (0.42) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL15194567 | 0.85 | SMN1; SMN2 (0.45) | POLBFKBP1ATP53SMN1; SMN2CNR1 | |
| SCHEMBL17001850 | 0.84 | FKBP1A (0.44) | POLBFKBP1ACNR1CNR2PEPD | |
| SCHEMBL20909019 | 0.84 | FKBP1A (0.44) | POLBFKBP1ACNR1CNR2PEPD | |
| SCHEMBL12881541 | 0.84 | FKBP1A (0.44) | POLBFKBP1ACNR1CNR2PEPD | |
| SCHEMBL1207488 | 0.83 | POLB (0.41) | POLBFKBP1ASMN1; SMN2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |