SCHEMBL24434718

SCHEMBL24434718

COC(=O)[C@H]1CCCN1C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
CNR1 P21554 4/20 0.44
CNR2 P34972 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
FKBP1A P62942 4/20 0.43
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
OGFRL1 Q5TC84 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
PKM P14618 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913398 0.93 POLB (0.46) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL2913400 0.93 POLB (0.46) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL6193034 0.91 SMN1; SMN2 (0.42) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL15194567 0.91 SMN1; SMN2 (0.45) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL24928818 0.91 POLB (0.42) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL15193817 0.89 SMN1; SMN2 (0.42) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL17001967 0.87 FKBP1A (0.42) POLBCNR1CNR2SMN1; SMN2FKBP1A
SCHEMBL17001850 0.86 FKBP1A (0.44) POLBCNR1CNR2FKBP1AALDH1A1
SCHEMBL12881541 0.86 FKBP1A (0.44) POLBCNR1CNR2FKBP1AALDH1A1
SCHEMBL20909019 0.86 FKBP1A (0.44) POLBCNR1CNR2FKBP1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153732-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153732-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G POLB 3636/4885CNR1 4399/4885CNR2 4727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.