SCHEMBL24929499

SCHEMBL24929499

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3sc3cccc(-c5cc(-c6ccc7oc8ccccc8c7c6)cc6sc7ccccc7c56)c34)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
BRDT Q58F21 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
PLA2G10 O15496 1/20 0.32
LIMK1 P53667 2/20 0.31
CHEK2 O96017 1/20 0.31
PRKDC P78527 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929418 0.91 PLA2G2A (0.32) ALOX5PLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL24929426 0.90 PLA2G2A (0.32) BRDTPLA2G2APLA2G4APLA2G10CHEK2
SCHEMBL24929623 0.90 LIMK1 (0.36) ALOX5BRDTPLA2G2APLA2G4APLA2G10
SCHEMBL22329920 0.89 LIMK1 (0.36) ALOX5PLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL23349809 0.89 ALOX5 (0.38) ALOX5BRDTPLA2G2APLA2G4APLA2G10
SCHEMBL22135463 0.88 PRKDC (0.39) ALOX5BRDTLIMK1PRKDCKDM4E
SCHEMBL24929476 0.88 ALOX5 (0.39) ALOX5BRDTLIMK1MAPT
SCHEMBL24929621 0.88 ALOX5 (0.36) ALOX5BRDTLIMK1PRKDCMAPT
SCHEMBL26223490 0.88 ALOX5 (0.35) ALOX5BRDTLIMK1ALOX15TSHR
SCHEMBL23822328 0.88 BRDT (0.36) ALOX5BRDTPLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008795-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-02-02 WO disclosed