SCHEMBL2492969

SCHEMBL2492969

NC(=O)c1nccnc1C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ADORA3 P0DMS8 1/20 0.48
MC4R P32245 1/20 0.48
ADRA1A P35348 1/20 0.48
MC3R P41968 1/20 0.48
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
ADORA2A P29274 2/20 0.38
PDPK1 O15530 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PRKCI P41743 2/20 0.36
MAP2K3 P46734 2/20 0.36
ATR Q13535 1/20 0.36
SIRT6 Q8N6T7 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931331 0.89 TSHR (0.46) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL13544700 0.89 ADORA3 (0.41) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL29693731 0.89 TSHR (0.46) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL30065824 0.84 PRKCI (0.48) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL161609 0.84 TSHR (0.41) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL1338425 0.84 TSHR (0.41) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL1097431 0.84 PRKCI (0.48) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL29379618 0.84 TSHR (0.41) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL22190220 0.83 HDAC1 (0.41) TSHRADORA3MC4RADRA1AMC3R
SCHEMBL24731313 0.82 TSHR (0.40) TSHRADORA3MC4RADRA1AMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106810769-A A kind of low temperature resistant PP composite material and preparation method thereof 宁夏润龙包装新材料股份有限公司 2017-06-09 CN claimed
US-9080068-B2 Gallium formulated ink and methods of making and using same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-07-14 US claimed
CN-102702841-B Gallium formulated ink and methods of making and using same ROHM & HAAS ELECT MAT 2015-01-14 CN claimed
CN-102643570-B Gallium ink and methods of making and using same ROHM AND HAAS ELECTRONIC MATERIALS CO., LTD. (US) 2014-10-29 CN claimed
US-8673401-B2 Gallium ink and methods of making and using same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-03-18 US claimed
US-20130122205-A1 Gallium Ink and Methods Of Making and Using Same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-05-16 US claimed
EP-2076573-B1 FLUOROPOLYMER COMPOSITIONS CONTAINING NITROGEN-CONTAINING AROMATIC MATERIALS 3M INNOVATIVE PROPERTIES CO (US) 2013-04-10 EP claimed
US-20130078384-A1 Gallium Formulated Ink and Methods Of Making and Using Same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-03-28 US claimed
US-8372485-B2 Gallium ink and methods of making and using same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-02-12 US claimed
US-8343267-B2 Gallium formulated ink and methods of making and using same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-01-01 US claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0684510-A1 Hybrid graphic arts films with reduced occurrence of pepper fog MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-29 EP claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0580880-A1 Control of anisotropic silicon etching utilizing a selected catalyzed etchant INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-02-02 EP claimed
US-3947442-A Method for producing heterocyclic acid anhydrides and pyrimidinediones THE SHERWIN-WILLIAMS COMPANY (US) 1976-03-30 US claimed