Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 6/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065824 | 1.00 | PRKCI (0.48) | PRKCIATRGRM5TLR7PDPK1 | |
| SCHEMBL2492969 | 0.84 | TSHR (0.48) | PRKCIATRGRM5PDPK1ADORA3 | |
| SCHEMBL27669301 | 0.82 | PRKCI (0.50) | PRKCIATRGRM5TLR7NAPRT | |
| SCHEMBL65106 | 0.80 | ATR (0.53) | PRKCIATRGRM5TLR7TSHR | |
| SCHEMBL20853598 | 0.80 | PRKCI (0.48) | PRKCIATRGRM5TLR7NAPRT | |
| SCHEMBL29578557 | 0.80 | ATR (0.53) | PRKCIATRGRM5TLR7TSHR | |
| SCHEMBL3292931 | 0.78 | PRKCI (0.47) | PRKCIATRGRM5TLR7NAPRT | |
| SCHEMBL30504248 | 0.78 | PRKCI (0.47) | PRKCIATRGRM5TLR7NAPRT | |
| Hydrochloric Acid SCHEMBL29522091 | 0.78 | ATR (0.52) | PRKCIATRGRM5TLR7TSHR | |
| SCHEMBL4569355 | 0.78 | PRKCI (0.47) | PRKCIATRGRM5TLR7NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| CN-117024413-B | 3-aminopyrazine-2-formamide targeted proteolytic chimera, and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117003736-B | 3-aminopyrazine-2-formamide targeted proteolytic chimera, and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-117024413-A | 3-aminopyrazine-2-formamide targeted proteolytic chimera, and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-117003736-A | 3-aminopyrazine-2-formamide targeted proteolytic chimera, and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2022-11-17 | — | — | US | claimed |
| CN-112654609-A | Amino-pyrazine carboxamide compounds, conjugates and uses thereof | 希沃尔拜克治疗公司 | 2021-04-13 | — | — | CN | claimed |
| CN-106699759-B | A kind of pteridine derivatives and contain its pharmaceutical composition | 李柱来 | 2019-07-19 | — | — | CN | claimed |
| CN-106699759-A | Pteridine derivative and pharmaceutical composition containing same | 李柱来 | 2017-05-24 | — | — | CN | claimed |
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |
| CN-100546580-C | Nicotine or nicotimine benzothiazole derivant | HOFFMANN LA ROCHE (CH) | 2009-10-07 | — | — | CN | claimed |
| CN-1617722-A | Nicotin-or isonicotin benzothiazole derivatives | HOFFMANN LA ROCHE (CH) | 2005-05-18 | — | — | CN | claimed |
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | claimed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | claimed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | claimed |
| JP-2304089-A | — | — | None | — | — | JP | disclosed |
| CN-122121515-A | Multifunctional organic additive doped CsSnI3Preparation and application of perovskite film | — | 2026-05-29 | — | — | CN | disclosed |
| JP-H02304089-A | 4(3H)-PTERIDINONE, ITS PRODUCTION, ANTIALLERGIC AGENT AND BRONCHOCONSTRICTION PREVENTIVE | LIPHA (LYON IND PHARMACEUT) | 1990-12-17 | — | — | JP | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |
| US-4361700-A | DIURETICS | Waldron, James S. (US) | 1982-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | TGFBR2, SMAD2, ACVR2A | PRKCI 4024/4885ATR 2222/4885GRM5 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.