Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 7/20 | 0.34 |
| ▸ | GSK3B | P49841 | 7/20 | 0.34 |
| ▸ | FLT3 | P36888 | 6/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930136 | 0.87 | GSK3A (0.33) | GSK3AGSK3BFLT3JAK2SRC | |
| SCHEMBL24929790 | 0.79 | GSK3A (0.49) | GSK3AGSK3BFLT3JAK2SRC | |
| SCHEMBL22149406 | 0.71 | JAK2 (0.30) | JAK2 | |
| SCHEMBL19259010 | 0.71 | GABBR2 (0.53) | KDRGABBR2GABBR1PDGFRBPDGFRA | |
| SCHEMBL24929792 | 0.67 | GSK3A (0.45) | GSK3AGSK3BFLT3JAK2SRC | |
| SCHEMBL22149395 | 0.66 | GSK3A (0.66) | GSK3AGSK3BFLT3JAK2SRC | |
| SCHEMBL24928785 | 0.66 | GSK3A (0.66) | GSK3AGSK3BFLT3JAK2SRC | |
| SCHEMBL20373994 | 0.63 | MEN1 (0.33) | — | |
| SCHEMBL5500778 | 0.61 | CHRNA7 (0.34) | JAK2 | |
| SCHEMBL17771553 | 0.60 | KMT2A (0.48) | JAK2GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009754-A2 | PROTEIN-ANTIVIRAL COMPOUND CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |