Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 13/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 13/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24929789 | 0.71 | GSK3A (0.34) | GABBR2GABBR1KDRPDGFRBPDGFRA | |
| SCHEMBL24929792 | 0.71 | GSK3A (0.45) | KDR | |
| SCHEMBL22149395 | 0.70 | GSK3A (0.66) | KDR | |
| SCHEMBL24928785 | 0.70 | GSK3A (0.66) | KDR | |
| SCHEMBL3123805 | 0.70 | GABBR2 (1.00) | GABBR2GABBR1 | |
| SCHEMBL3123795 | 0.70 | GABBR2 (1.00) | GABBR2GABBR1 | |
| SCHEMBL3119355 | 0.70 | GABBR2 (1.00) | GABBR2GABBR1 | |
| SCHEMBL3119366 | 0.70 | GABBR2 (1.00) | GABBR2GABBR1 | |
| SCHEMBL3119363 | 0.70 | GABBR2 (1.00) | GABBR2GABBR1 | |
| SCHEMBL20404182 | 0.69 | KMT2A (0.48) | GABBR2GABBR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |