SCHEMBL24929935

SCHEMBL24929935

CCCC(CNC=O)NCNC=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 4/20 0.41
ADH1A P07327 4/20 0.41
ADH1C P00326 3/20 0.41
ADH7 P40394 3/20 0.38
EPHX1 P07099 1/20 0.34
ADH4 P08319 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10048338 0.79 ADH1B (0.44) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL27667488 0.79 ADH1B (0.44) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL8628353 0.72 ADH1B (0.50) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL13950294 0.72 ADH1B (0.50) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL269153 0.70
SCHEMBL8693116 0.68 TSHR (0.46) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL28310278 0.68 ADH1B (0.46) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL25604176 0.67 ADH1B (0.50) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL8627522 0.66 ADH1B (0.46) ADH1BADH1AADH1CADH7EPHX1
SCHEMBL6050817 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122926-A1 TRIAZINE DERIVATIVE HAVING VIRUS PROPAGATION INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Shionogi & Co., Ltd (JP) 2023-01-25 EP disclosed