⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933081 | 0.81 | HOGA1 (0.33) | — | |
| SCHEMBL18535564 | 0.79 | HOGA1 (0.33) | — | |
| SCHEMBL24933078 | 0.79 | HOGA1 (0.33) | — | |
| SCHEMBL18535650 | 0.79 | HOGA1 (0.33) | — | |
| SCHEMBL19929869 | 0.79 | THRB (0.33) | — | |
| SCHEMBL18530077 | 0.79 | THRB (0.33) | — | |
| SCHEMBL22519824 | 0.79 | THRB (0.33) | — | |
| SCHEMBL18535664 | 0.78 | MAN1B1 (0.36) | — | |
| SCHEMBL13074653 | 0.78 | — | — | |
| SCHEMBL18535554 | 0.78 | FUCA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009554-A1 | METHODS TO REDUCE ADVERSE EFFECTS OF GENE OR BIOLOGICS THERAPY | AVILAR THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |