Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 9/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933007 | 0.84 | PPARD (0.44) | HSD17B2HSD17B1PTGDR2SRD5A2PRKAB2 | |
| SCHEMBL24933256 | 0.82 | PDK2 (0.43) | HSD17B2HSD17B1MOGAT2PRKAB2PRKAG1 | |
| SCHEMBL24932956 | 0.81 | FYN (0.45) | HSD17B2HSD17B1SCN9AMAPTBLM | |
| SCHEMBL24933416 | 0.81 | HSD17B1 (0.36) | HSD17B2HSD17B1SCN9AMOGAT2 | |
| SCHEMBL24933847 | 0.81 | CHEK1 (0.46) | HSD17B2HSD17B1SCN9AMOGAT2PRKAB2 | |
| SCHEMBL24933357 | 0.80 | TSHR (0.43) | MAPTBLMGPR55ALDH1A1 | |
| SCHEMBL24933053 | 0.80 | KDM4E (0.44) | HSD17B2HSD17B1MAPTPTGDR2ALDH1A1 | |
| SCHEMBL24933212 | 0.78 | HSD17B1 (0.34) | HSD17B2HSD17B1SCN9AMAPTBLM | |
| SCHEMBL24933418 | 0.78 | MOGAT2 (0.41) | HSD17B2HSD17B1SCN9AALDH1A1MOGAT2 | |
| SCHEMBL29203411 | 0.78 | SCN9A (0.36) | HSD17B2HSD17B1SCN9ASRD5A2PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |