Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933257 | 0.87 | P2RX3 (0.39) | — | |
| SCHEMBL24933705 | 0.87 | P2RX3 (0.39) | — | |
| SCHEMBL24933656 | 0.87 | CHEK2 (0.43) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL24933789 | 0.85 | CHEK2 (0.42) | — | |
| SCHEMBL24933356 | 0.84 | PARP10 (0.52) | — | |
| SCHEMBL24933004 | 0.84 | IRAK4 (0.44) | — | |
| SCHEMBL30240709 | 0.83 | HSD17B2 (0.35) | — | |
| SCHEMBL24933826 | 0.83 | HSD17B2 (0.35) | — | |
| SCHEMBL24933633 | 0.83 | PARP10 (0.53) | — | |
| SCHEMBL29203336 | 0.82 | CHEK2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |